DOUXO S3 PYO pads moving to DOUXO S3 CALM pads

Your pet’s skin has settled. What comes next? From DOUXO® S3 PYO to CALM

By
✔ BVMS
MRCVS
Updated October 07, 2026
3 min read

Step one: the flare-up

Beyond the flare-up

Step two: everyday care

Making the switch

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DOUXO S3 PYO pads moving to DOUXO S3 CALM pads

Your pet’s skin has settled. What comes next? From DOUXO® S3 PYO to CALM

By
✔ BVMS
MRCVS
Updated October 07, 2026
3 min read

If your pet has been using DOUXO® S3 PYO to get a skin flare-up under control, you might be wondering what comes next. Once their skin has settled, it’s time to think about maintenance, and that’s where DOUXO® S3 CALM comes in.

For pets prone to sensitive or allergic skin, it’s easy to think the problem has gone once the skin has calmed down. Ongoing care can make all the difference, helping keep skin healthy and better protected rather than waiting for the next flare-up. Our Joii team is available 24 hours a day for advice.

Step one: getting the flare-up under control

When your pet’s skin problem flares up, it can lead to an overgrowth of bacteria or yeast.

  • This can make inflammation and itching worse and contribute to skin infections.

  • An antiseptic, such as chlorhexidine, can help reduce these microorganisms and bring the skin back to its normal, healthy balance.

That’s where DOUXO® S3 PYO comes in.

Why treating the flare-up is only the first step

Many skin problems, including atopic dermatitis in dogs and cats, are long-term conditions where flare-ups come and go. The cycle often begins with a weakened skin barrier.

The itch, scratch and inflammation cycle
The flare-up cycle
It often starts with a weakened skin barrier.
When the skin barrier is damaged, moisture can escape, and allergens, irritants and microbes can enter the skin surface more readily. This can worsen inflammation and itching, creating a frustrating cycle: itch, scratch, more inflammation, and round again.

Step two: everyday care with DOUXO® S3 CALM

DOUXO® S3 CALM contains a high concentration of Ophytrium, which:

  • Helps strengthen the skin barrier.

  • Helps maintain a balanced skin microbiome.

  • Soothes irritation and inflammation.

That makes it ideal for regular maintenance. It helps address some of the underlying issues that allow problems to develop in the first place, and reduces the risk of future flare-ups.

DOUXO® S3 CALM is also available as a shampoo, mousse and shampoo bar. If you’re using the shampoo or shampoo bar as part of your pet’s routine, our guide on how to bathe your dog covers what to use and how often.

When it flares up
DOUXO® S3 PYO
Purifying and hydrating. Contains chlorhexidine to reduce excess bacteria and yeast.
Once it’s settled
DOUXO® S3 CALM
Soothing, for itchy and irritated skin. Ophytrium supports the skin barrier for ongoing care.
“
Once your pet has completed their recommended DOUXO® S3 PYO treatment and no longer needs antiseptic care, CALM may be a helpful next step. It supports sensitive skin and ongoing comfort.
Dr Chantal Serra, Joii vet

Is it time to make the switch?

Dr Ann Draper, Joii vetDr Nienke Oostra, Joii vetDr Valter Carlos, Joii vetDr Carolina Paz, Joii vet+
Joii vets, 24 hours a day
Not sure if it’s time? Ask one of our vets.
Every pet is different. Switch once your pet’s skin has settled, and if you’re not sure whether they’re ready, a Joii vet can look at how things are going and help you decide.
Speak to a Joii vet →
DOUXO® S3 Calm Pads
Your next step
DOUXO® S3 Calm Pads
Soothing pads for itchy, irritated skin. Everyday care to keep skin settled.
10% off your first delivery, then £9.49 (5% off) every time.

Speak to one of our Joii vets if:

  • You’re not sure whether your pet’s skin has settled enough to switch

  • Your pet’s skin flares up again after switching

  • You’d like advice on which DOUXO® S3 format suits your pet

  • You want advice on managing your pet’s sensitive skin at home

Always follow your vet’s advice, particularly if your pet has been diagnosed with an allergy or recurring skin problem. If your pet develops new, persistent or worsening skin issues, speak to a vet.

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